Dr Lindsay Wu is a metabolic biochemist and American Federation for Aging Research (AFAR) / Hevolution Investigator at UNSW Sydney. His lab studies the molecular and metabolic mechanisms that underlie biological ageing, with a focus on applications for female fertility. A key interest for the lab is the role of altered metabolism as a cause of reproductive ageing, including using stable isotope tracing approaches to explore unexpected mechanisms for the biosynthesis of the redox cofactor nicotinamide adenine dinucleotide (NAD+). His group previously showed that declining levels of this cofactor are a reversible cause of reproductive ageing in mice, resulting in ongoing clinical translation, and other ongoing research includes its applications in chemotherapy induced infertility and late-life female health.